According to Emily McDonald Evens, of
the Department of Public Health, University of North Carolina at Chapel
Hill, though fertility is a global problem, it is an under-recognised
public health issue which can no longer remain so.
She also notes that individuals and
couples suffering from unwanted childlessness experience significant, at
times life-threatening, consequences. And because of the extended
family system that is practised in most parts of Africa, including
Nigeria, childlessness does not remain the problem of the affected
couples alone and it can tear families apart.
Most couples assume that pregnancy will
occur soon after discontinuing contraception. They scrutinise their
behaviours, habits, and lifestyle to try to understand why they have not
been able to conceive. They also examine the timing, frequency, and
technique of intercourse to explain why they have not been able to
conceive.
Experts say infertility is a disease of
the reproductive system which affects both men and women with almost
equal frequency. They argue that it is a global phenomenon, with some
portion of every human population affected.
It is estimated that an average of 10
per cent of the global reproductive-age population is unable to get
pregnant or carry a pregnancy to term. And while there is no universal
definition of infertility, a couple is generally considered clinically
infertile when pregnancy has not occurred after at least 12 months of
regular sexual activity without the use of contraceptives.
Primary infertility is defined as
childlessness and secondary infertility as the inability to have an
additional live birth for a parous woman – that is, a woman who has had a
child before.
The Global Library of Women’s Medicine
describes infertility as a life crisis, underscoring the frustrations
that families experience when they cannot reproduce as expected.
Women often assume that they are the
cause of the infertility and search their past for a potential cause.
Women who have had a sexually transmitted disease or previous abortion
may be convinced that the infertility is a result of those events. This
may lead them to feel guilty and question their worthiness as a wife and
a potential mother. Less often, the man may wonder if a past medical
condition, medication, or habit may be compromising his fertility. When
the couple continues to have difficulty conceiving, most seek medical
advice and treatment, including trying to find an explanation for their
problem.
At some time during the infertility
evaluation and treatment, couples may feel intense anger. They may argue
that life has treated them unfairly and that their infertility is
unjust. They may become intensely angry when they see individuals, whom
they believe undeserving, achieve a pregnancy with little or no effort.
They may feel very angry when they hear a pregnant woman display disgust
or unhappiness with her pregnancy; when they see women with an unwanted
pregnancy seeking an abortion; or when they observe a mother or father
abusing their child.
Despite all the advances that the human
race has experienced in the treatment of infertility, the issue is still
treated as a taboo, and couples actually find it difficult to disclose
the causes of their challenges until they are forced to do so when the
problem can no longer be hidden.
Worse still, many of the assisted
reproductive technologies are so expensive that they are beyond the
earning capability of most couples. Fertility experts say that on the
average, an in-vitro fertilisation process costs about N250,000,
depending on the age of the couple, the state of their health, etc.
Worse still, the rate of success for IVF
is still about 45 per cent; as such, an individual can undergo five
cycles or more without achieving pregnancy. When this happens, it is not
only frustrating, it drains the couples of their hard earned money,
wastes time and wreaks psychological havoc on them.
When couples are infertile, they feel a
sense of loss of self-esteem, relationships, health, and financial
security. All these add to their woes. This ought not to be so, as the
medical sciences have made it possible for infecund couples to achieve
their dream of raising a family through natural remedies that have very
little or no side effects, affordable and reassuring.
Fidson Healthcare Plc, foremost Nigerian
pharmaceutical giant, has developed two drugs that those who have had
access to them say are effective in the treatment of both primary and
secondary infertility. They are Addyzoa for men and M2-Tone for women.
Addyzoa has been indicated in the
management of male infertility, as it is estimated that in
approximately 30 per cent of infertile couples, the ‘fault’ lies with
the male; in another 20 per cent, both male and female factors are
responsible. Thus, in around half of all infertile couples, male-factor
infertility plays a part in the inability to conceive a child.ameters are important causes of male-factor infertility, though there
is a large group of men for whom no cause can be identified.
The list of conventional medicines for non-specific therapy is long and includes clomiphene, tamoxifen, and mesterolone. Success rates varying from 10 to 50 per cent have been reported with these agents, but overall, results remain poor.
Addyzoa is an Ayurvedic medicine
which has been widely used for the empirical treatment of male
infertility for more than three decades and still counting. In other
words, its success has been proved over and again in treating male
infertility.
To test the efficacy of Addyzoa, a
total of 50 patients with male-factor infertility of no known cause
attending the Malhotra Test Tube Baby Centre and Agra Andrology Centre
in India were recruited in the present study.
On the basis of routine clinical
examination, semen analysis, and, where necessary, further
investigations (including sperm function tests, anti-sperm antibody
tests, blood hormone profile, and scrotal ultrasound scan to rule out
varicocele), all were diagnosed with male infertility of no known cause.
The patients were then randomly assigned in a double-blind fashion to treatment with Addyzoa
or placebo (oral administration of two capsules twice daily for three
months). The two groups were equally sized, each containing 25 patients.
Repeat semen analysis was conducted at monthly intervals, with sperm
density, motility, and morphology being evaluated.
At the end of the day, there was an improvement in sperm density in 84 per cent of patients on Addyzoa, compared with 52 per cent of patients on placebo.
In the case of M2-Tone, which is
used to treat female infertility, a study was conducted on 50 women of
unexplained infertility. Twenty-five each were administered M2-Tone syrup and placebo to scientifically reassess efficacy at a primary level.
M2-Tone syrup is a herbomineral
formulation blended with 47 natural chemically active ingredients, known
for their efficacy in various gynaecological disorders. The results
showed 33.3 per cent conception rate, with full safety in M2-Tone group; while only one conception was recorded in the placebo group.
Additionally, in 36.3 per cent women, M2-Tone
cured menstrual irregularities. All the women with menorrhagia and
hypomenorrhoea and 75 per cent with spasmodic dysmenorrhoea responded
favourably. The mechanism by which M2-Tone acts is by its proven “estrogenic” effect on the female reproductive system.
Addyzoa and M2-Tone are distributed exclusively by Fidson Healthcare Plc in Nigeria, and they are available in pharmaceutical stores.
Doctors say medicines must be taken under professional supervision.
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